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Jonathan Downar, MD, Ph.D., MD PhD FRCPC

Dr. Downar serves as the Director of the MRI-Guided rTMS Clinic at University Health Network, and also holds the position of Scientist at the Toronto Western Research Institute.  He completed a BSc in biology at McGill University, followed by a Ph.D. in neuroimaging at the University of Toronto with Dr. Karen Davis, before obtaining his medical degree from the University of Calgary in 2005.  He then returned to Toronto for his psychiatry residency training, during which he also completed a research fellowship in neuroeconomics with Dr. Read Montague at Baylor College of Medicine.

Dr. Downar joined the Department of Psychiatry at UHN on completion of his residency in 2010.  Shortly thereafter, he established the MRI-Guided rTMS Clinic, with a mandate to accept referrals from the community as a clinical resource, while simultaneously conducting translational research into improving the efficacy, cost, access, and range of indications for non-invasive brain stimulation in psychiatric illness. The UHN clinic now includes 4 treatment suites, treats volumes of 50-60 patients daily, and receives >500 referrals/year.  The UHN clinic works in close collaboration with Drs. Daskalakis and Blumberger at the Temerty Centre at CAMH.

Dr. Downar's research work focuses on translating advances in basic neuroimaging and neuroscience research into improvements in the efficacy, capacity, and cost of rTMS.  His lab also seeks to identify better targets for rTMS across a wider range of conditions and to identify neuroimaging biomarkers to predict the best treatment parameters for individual patients presenting for treatment.  He currently holds an operating grant from CIHR as well as peer-reviewed funding from Brain Canada, the Klarman Foundation, and the Edgestone Foundation. His work has been published in Biological Psychiatry, Neuropsychopharmacology, Brain Stimulation, and Nature Neuroscience.