TMS can be very effective in the treatment of depression. For over 20 years it has demonstrated the ability to improve depression symptoms in patients in research studies as well as under more real-world conditions. In one of the largest studies of patients treated with TMS for depression, around 60% of participants reduced their symptoms by at least 50% (responded) and around 30% of participants no longer met criteria for depression (remitted). This study did include some participants who have been treated with ECT to manage their symptoms and they had equal chances to achieve improvement compared to people who had not had ECT in the past. TMS is effective in the treatment of obsessive-compulsive disorder (OCD) as well. Around 40% of participants in the landmark study for FDA (Food and Drug Administration) clearance achieved remission and around 60% of participants responded to treatment. This is just a sample of some of the illnesses that TMS has been demonstrated to effectively treat but there are other illnesses that are under investigation or approved in countries outside of the United States including PTSD, stroke rehabilitation, and chronic pain.