Since 2018, CTMSS has provided a speaking platform for the Top 4 Poster Abstracts at the Annual Meeting. We are thrilled to be able to continue to share our top research and findings.
The Abstract Review Committee decided to include an additional two abstracts this year to be presented since the 2020 Annual Meeting in Chicago was regrettably canceled. These abstracts were originally scheduled as general presentations for the conference and as such, were not eligible for being selected to present during this session. Thus, this year there was a total of 6 top abstracts presented.
Anhedonia is a severely debilitating hallmark feature of Major Depressive Disorder (MDD) and a symptom which is often difficult to treat. Snaith-Hamilton Pleasure Scale (SHAPS), a validated 14-question self-assessment for anhedonia, was collected in a naturalistic setting before and after TMS for treatment-resistant MDD. TMS resulted in a significant improvement in hedonic drive from pre to post TMS overall. Patients whose MDD met response criteria had a significantly greater degree of improvement in hedonic drive. However, baseline anhedonia severity was not a predictor of TMS clinical response.